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Silver no_smiles Hydroxylation

CYP76M6

Oryza sativa CYP76M

Poaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
syn-stemodene
PubChem ↗ C[C@]12CCCC([C@@H]1CC[C@@H]3[C@]24CCC(=C)[C@@H](C3)C4)(C)C
CYP76M6
ΔMass: no_smiles Missing dual SMILES or RDKit not validated
Product
6β-hydroxy-syn-stemodene
PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; PMID 22215681, recombinant expression in E. coli, in vitro assay with microsomes, GC-MS and NMR characterization.

Reaction & quality gates

Mechanism
Hydroxylation
Evidence type
In vitro
Confidence
High
Data tier
Silver
mass=no_smiles; incomplete_SMILES
Substrate class
Other
Product class
Other

Literature & public identifiers

PubMed
PMID:22215681 ↗
DOI
10.1074/jbc.m111.305599 ↗
UniProt
Q6Z5I7 ↗
GenBank
NCBI TaxID
4530 ↗

Characterization of CYP76M5-8 indicates metabolic plasticity within a plant biosynthetic gene cluster.