Bronze
no_smiles
Hydroxylation
Substrate reaction site
Product reaction site
MCS substructure diff highlighting · RDKit atom mapping
C3H
ΔMass: no_smiles
Missing dual SMILES or RDKit not validated
Product
caffeoyl-shikimate
PubChem ↗
CC(=O)OC1=C(C=C(C=C1)/C=C/C(=O)O[C@@H]2CC(=C[C@H]([C@H]2O)O)C(=…
Evidence trail
Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.
Source text excerpt ation; ation; C3H (p-coumaroyl shikimate/quinate 3-hydroxylase) is a cytochrome P450 (CYP98A) that catalyzes the 3-hydroxylation of p-coumaroyl shikimate. The paper includes C3H in the capsaicinoid biosynthetic pathway (Figure 3a) but does not provide direct experimental evidence for this reaction in Capsicum annuum.
Reaction & quality gates
- Mechanism
- Hydroxylation
- Evidence type
- Pathway_inference
- Confidence
- Medium
- Data tier
- Bronze
evidence=Pathway_inference - Substrate class
- Other
- Product class
- Other
Literature & public identifiers
- PubMed
- PMID:24441736 ↗
- DOI
- 10.1038/ng.2877 ↗
- UniProt
- A0A0K8WMK1 ↗
- GenBank
- —
- NCBI TaxID
- 4072 ↗
Genome sequence of the hot pepper provides insights into the evolution of pungency in Capsicum species.