CYP76AD1

Hatlestad et CYP76A

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

L-DOPA

PubChem ↗ C1=CC(=C(C=C1C[C@@H](C(=O)O)N)O)O

CYP76AD1

ΔMass: -2.0157 Da ketone_formation(-2.0157)

Product

cyclo-DOPA

PubChem ↗ C1[C@H](NC2=CC(=C(C=C21)O)O)C(=O)O

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; CYP76AD1 catalyzes the formation of cyclo-DOPA from L-DOPA, as described in the abstract and text (Hatlestad et al., 2012).

Reaction & quality gates

Mechanism: Ketone formation (-2.02 Da)
Evidence type: In vitro
Confidence: High
Data tier: Gold
Latin binomial + experiment + dual SMILES + ΔMass pass
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:25966996 ↗
DOI: 10.1111/nph.13441 ↗
UniProt: KR376500 ↗
GenBank: KR376500 ↗
NCBI TaxID: —

Lineage-specific gene radiations underlie the evolution of novel betalain pigmentation in Caryophyllales.