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Quarantine no_smiles Cyclization

SfCPS

Salvia fruticosa

Lamiaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
geranylgeranyl diphosphate
PubChem ↗ CC(=CCC/C(=C/CC/C(=C/CC/C(=C/COP(=O)(O)OP(=O)(O)O)/C)/C)/C)C
SfCPS
ΔMass: no_smiles Missing dual SMILES or RDKit not validated
Product
copalyldiphosphate
PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ization; ization; Coupled transient expression in Nicotiana benthamiana with SfKSL, leading to miltiradiene production (indirect evidence of CDP formation).

Reaction & quality gates

Mechanism
Cyclization
Evidence type
In vivo
Confidence
High
Data tier
Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class
Other
Product class
Other

Literature & public identifiers

PubMed
PMID:26020634 ↗
DOI
10.1371/journal.pone.0124106 ↗
UniProt
KP091840 ↗
GenBank
KP091840 ↗
NCBI TaxID
268906 ↗

Towards Elucidating Carnosic Acid Biosynthesis in Lamiaceae: Functional Characterization of the Three First Steps of the Pathway in Salvia fruticosa and Rosmarinus officinalis.