Quarantine
no_smiles
Cyclization
Substrate reaction site
Product reaction site
MCS substructure diff highlighting · RDKit atom mapping
SfKSL
ΔMass: no_smiles
Missing dual SMILES or RDKit not validated
Evidence trail
Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.
Source text excerpt ization; ization; Coupled in vitro assay with SfCPS and GGDP; product identified as miltiradiene by GC-MS and NMR.
Reaction & quality gates
- Mechanism
- Cyclization
- Evidence type
- In vitro
- Confidence
- High
- Data tier
- Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450) - Substrate class
- Other
- Product class
- Terpenoids
Literature & public identifiers
- PubMed
- PMID:26020634 ↗
- DOI
- 10.1371/journal.pone.0124106 ↗
- UniProt
- KP091841 ↗
- GenBank
- KP091841 ↗
- NCBI TaxID
- 268906 ↗
Towards Elucidating Carnosic Acid Biosynthesis in Lamiaceae: Functional Characterization of the Three First Steps of the Pathway in Salvia fruticosa and Rosmarinus officinalis.