CYP726A27

Euphorbia lathyris CYP726A

Euphorbiaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

9-hydroxycasbene

PubChem ↗ C/C/1=C\CC(/C(=C/CC/C(=C/[C@@H]2[C@@H](C2(C)C)CC1)/C)/C)O

CYP726A27

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

5,9-casbene diol

PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; CYP726A27 catalyzes 5-hydroxylation of 9-hydroxycasbene to form 5,9-casbene diol; inferred from in vitro microsomal assays with compound 6.

Reaction & quality gates

Mechanism: Hydroxylation
Evidence type: In vitro
Confidence: Medium
Data tier: Silver
mass=no_smiles; incomplete_SMILES
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:27506796 ↗
DOI: 10.1073/pnas.1607504113 ↗
UniProt: KR350669 ↗
GenBank: KR350669 ↗
NCBI TaxID: 212925 ↗

Oxidation and cyclization of casbene in the biosynthesis of Euphorbia factors from mature seeds of Euphorbia lathyris L.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme