Silver
no_smiles
Oxidation
Substrate reaction site
Product reaction site
MCS substructure diff highlighting · RDKit atom mapping
CYP71D445
ΔMass: no_smiles
Missing dual SMILES or RDKit not validated
Product
5-hydroxy-9-ketocasbene
PubChem ↗
C/C/1=C\CC(=O)/C(=C/CC(/C(=C/[C@@H]2[C@@H](C2(C)C)CC1)/C)O)/C
Evidence trail
Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.
Source text excerpt ation; ation; CYP71D445 oxidizes the 9-hydroxyl group of 5,9-casbene diol to 9-ketone; confirmed by in vitro microsomal assays.
Reaction & quality gates
- Mechanism
- Oxidation
- Evidence type
- In vitro
- Confidence
- Medium
- Data tier
- Silver
mass=no_smiles; incomplete_SMILES - Substrate class
- Other
- Product class
- Other
Literature & public identifiers
- PubMed
- PMID:27506796 ↗
- DOI
- 10.1073/pnas.1607504113 ↗
- UniProt
- KR350668 ↗
- GenBank
- KR350668 ↗
- NCBI TaxID
- 212925 ↗
Oxidation and cyclization of casbene in the biosynthesis of Euphorbia factors from mature seeds of Euphorbia lathyris L.