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Silver no_smiles Hydroxylation

CYP71BE79

Gossypium hirsutum CYP71B

Malvaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
8-hydroxy-7-keto-d-cadinene
PubChem ↗ Cc1cccc(Cl)n1
CYP71BE79
ΔMass: no_smiles Missing dual SMILES or RDKit not validated
Product
8,11-dihydroxy-7-keto-d-cadinene
PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; CYP71BE79 catalyzes the hydroxylation of C234 (8-hydroxy-7-keto-d-cadinene) to 8,11-dihydroxy-7-keto-d-cadinene; enzyme activity described as exceptionally high in vitro (ref 13).

Reaction & quality gates

Mechanism
Hydroxylation
Evidence type
In vitro
Confidence
High
Data tier
Silver
mass=no_smiles; incomplete_SMILES
Substrate class
Other
Product class
Other

Literature & public identifiers

PubMed
PMID:30967019 ↗
DOI
10.1098/rstb.2018.0319 ↗
UniProt
GenBank
NCBI TaxID
3635 ↗

A gossypol biosynthetic intermediate disturbs plant defence response.