CYP90B50

Repeated evolution CYP90B

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

16S,22S-dihydroxycholesterol

PubChem ↗ C[C@@H]([C@H]1[C@H](C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC…

CYP90B50

ΔMass: -2.0157 Da ketone_formation(-2.0157)

Product

16-hydroxy-22-oxo-cholesterol

PubChem ↗ CC(C)CCC(=O)[C@@H](C)[C@H]1C(O)C[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Inferred from LC-MS and chemical logic; compound 5.

Reaction & quality gates

Mechanism: Ketone formation (-2.02 Da)
Evidence type: In vitro
Confidence: Medium
Data tier: Gold
Latin binomial + experiment + dual SMILES + ΔMass pass
Substrate class: Steroids
Product class: Steroids

Literature & public identifiers

PubMed: PMID:31324795 ↗
DOI: 10.1038/s41467-019-11286-7 ↗
UniProt: XP_015619622 ↗
GenBank: XP_015619622 ↗
NCBI TaxID: —

Repeated evolution of cytochrome P450-mediated spiroketal steroid biosynthesis in plants.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme