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Silver no_smiles Hydroxylation

CYP81F2

Arabidopsis thaliana CYP81F

Brassicaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
indolic glucosinolate
PubChem ↗ Crowdsource substrate structure
CYP81F2
ΔMass: no_smiles Missing dual SMILES or RDKit not validated
Product
4-hydroxyindol-3-ylmethylglucosinolate
PubChem ↗ C1=CC2=C(C(=C1)O)C(=CN2)CC(=NOS(=O)(=O)O)S[C@H]3[C@@H]([C@H]([C…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; CYP81F2 is a member of the CYP81F subfamily involved in glucosinolate metabolism; loss-of-function mutants exhibit compromised fungal resistance. The specific substrate and product are inferred from known glucosinolate pathway (4-hydroxyindol-3-ylmethylglucosinolate). Evidence from transcriptomic and mutant studies in Arabidopsis thaliana.

Reaction & quality gates

Mechanism
Hydroxylation
Evidence type
In vivo
Confidence
Medium
Data tier
Silver
mass=no_smiles; incomplete_SMILES
Substrate class
Glucosinolates
Product class
Glucosinolates

Literature & public identifiers

PubMed
PMID:40729005 ↗
DOI
10.3390/cimb47070536 ↗
UniProt
C3W7I0 ↗
GenBank
NCBI TaxID
3702 ↗

Transcriptomic Analysis Reveals Candidate Hub Genes and Putative Pathways in <i>Arabidopsis thaliana</i> Roots Responding to <i>Verticillium longisporum</i> Infection.