CYP72A63

Establishing cell CYP72A

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

11-oxo-beta-amyrin

PubChem ↗ C[C@@]12CC[C@@]3(C(=CC(=O)[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](…

CYP72A63

ΔMass: +13.9793 Da mismatch

Product

glycyrrhetaldehyde

PubChem ↗ C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; CYP72A63 oxidizes C-30 of 11-oxo-beta-amyrin; source_organism set to NEEDS_SALVAGE.

Reaction & quality gates

Mechanism: Oxidation
Evidence type: In vitro
Confidence: High
Data tier: Silver
mass=mismatch
Substrate class: Terpenoids
Product class: Other

Literature & public identifiers

PubMed: PMID:39309497 ↗
DOI: 10.1016/j.apsb.2024.04.032 ↗
UniProt: H1A981 ↗
GenBank: —
NCBI TaxID: —

Establishing cell suitability for high-level production of licorice triterpenoids in yeast.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme