CYP72A63

Establishing cell CYP72A

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

glycyrrhetaldehyde

PubChem ↗ C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC…

CYP72A63

ΔMass: +15.9949 Da hydroxylation(+15.9949)

Product

glycyrrhetinic acid

PubChem ↗ C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; CYP72A63 catalyzes consecutive oxidation; source_organism set to NEEDS_SALVAGE.

Reaction & quality gates

Mechanism: Hydroxylation (+15.99 Da)
Evidence type: In vitro
Confidence: High
Data tier: Gold
Latin binomial + experiment + dual SMILES + ΔMass pass
Substrate class: Other
Product class: Organic acids

Literature & public identifiers

PubMed: PMID:39309497 ↗
DOI: 10.1016/j.apsb.2024.04.032 ↗
UniProt: H1A981 ↗
GenBank: —
NCBI TaxID: —

Establishing cell suitability for high-level production of licorice triterpenoids in yeast.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme