CYP712K2

Tripterygium wilfordii CYP712K

Celastraceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

celastrol precursor

PubChem ↗ Crowdsource substrate structure

CYP712K2

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

celastrol

PubChem ↗ CC1=C(C(=O)C=C2C1=CC=C3[C@]2(CC[C@@]4([C@@]3(CC[C@@]5([C@H]4C[C…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; TwCYP712K1 and TwCYP712K2 are involved in celastrol biosynthesis in Tripterygium wilfordii (Table 1).

Reaction & quality gates

Mechanism: Oxidation
Evidence type: Pathway_inference
Confidence: High
Data tier: Bronze
evidence=Pathway_inference
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:40364345 ↗
DOI: 10.3390/plants14091316 ↗
UniProt: QYZ87004.1 ↗
GenBank: CYP712K2 ↗
NCBI TaxID: 458696 ↗

Application and Progress of Genomics in Deciphering the Genetic Regulation Mechanisms of Plant Secondary Metabolites.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme