MnCHS

Morus notabilis

Moraceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

p-coumaroyl-CoA

PubChem ↗ CC(C)(COP(=O)(O)OP(=O)(O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3…

MnCHS

ΔMass: -641.0835 Da mismatch

Product

naringenin

PubChem ↗ C1[C@H](OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ization; ization; MnCHS converts p-coumaroyl-CoA to naringenin via chalcone intermediate; in vitro enzyme assay with purified recombinant protein.

Reaction & quality gates

Mechanism: Cyclization
Evidence type: In vitro
Confidence: High
Data tier: Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class: Other
Product class: Phenylpropanoids

Literature & public identifiers

PubMed: PMID:41112970 ↗
DOI: 10.1093/hr/uhaf171 ↗
UniProt: PV023578 ↗
GenBank: PV023578 ↗
NCBI TaxID: 981085 ↗

Functional characterization of key enzymes involved in the biosynthesis of distinctive flavonoids and stilbenoids in <i>Morus notabilis</i>.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme