← Back to reactions
Quarantine mismatch Cyclization

MnCHS

Morus notabilis

Moraceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
2,4-dihydroxycinnamoyl-CoA
PubChem ↗ CC(C)(COP(=O)([O-])OP(=O)([O-])OC[C@@H]1[C@H]([C@H]([C@@H](O1)N…
MnCHS
ΔMass: -637.0544 Da mismatch
Product
steppogenin
PubChem ↗ C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=C(C=C(C=C3)O)O

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ization; ization; MnCHS converts 2,4-dihydroxycinnamoyl-CoA to steppogenin; in vitro enzyme assay with purified recombinant protein.

Reaction & quality gates

Mechanism
Cyclization
Evidence type
In vitro
Confidence
High
Data tier
Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class
Other
Product class
Other

Literature & public identifiers

PubMed
PMID:41112970 ↗
DOI
10.1093/hr/uhaf171 ↗
UniProt
PV023578 ↗
GenBank
PV023578 ↗
NCBI TaxID
981085 ↗

Functional characterization of key enzymes involved in the biosynthesis of distinctive flavonoids and stilbenoids in <i>Morus notabilis</i>.