Silver
no_smiles
Hydroxylation
Substrate reaction site
Product reaction site
MCS substructure diff highlighting · RDKit atom mapping
NdsC
ΔMass: no_smiles
Missing dual SMILES or RDKit not validated
Evidence trail
Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.
Source text excerpt ation; ation; NdsC hydroxylates the 3-methyl group of the 3-MOA unit in duricamidepside (compound 2) to produce hydroxy-duricamidepside (compound 9). Evidence from heterologous expression of ndsABC in A. nidulans.
Reaction & quality gates
- Mechanism
- Hydroxylation
- Evidence type
- In vivo
- Confidence
- High
- Data tier
- Silver
mass=no_smiles; incomplete_SMILES - Substrate class
- Other
- Product class
- Other
Literature & public identifiers
- PubMed
- PMID:41122484 ↗
- DOI
- 10.1039/d5sc05442g ↗
- UniProt
- —
- GenBank
- —
- NCBI TaxID
- —
Heterologous expression of an <i>in planta</i>-upregulated gene cluster in the wheat pathogen <i>Parastagonospora nodorum</i> establishes the biosynthesis of methylene-bridged depsides.