HYC3O

Rauvolfia tetraphylla

Apocynaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

alloyohimbine

PubChem ↗ COC(=O)[C@H]1[C@H](CC[C@H]2[C@@H]1C[C@H]3C4=C(CCN3C2)C5=CC=CC=C…

HYC3O

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

3-dehydro-alloyohimbine

PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Rauvolfia tetraphylla HYC3O; purified recombinant protein; LC-MS/MS and UV confirmed.

Reaction & quality gates

Mechanism: Oxidation
Evidence type: In vitro
Confidence: High
Data tier: Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:41290611 ↗
DOI: 10.1038/s41467-025-65543-z ↗
UniProt: —
GenBank: —
NCBI TaxID: 545371 ↗

Ancient gene clusters govern the initiation of monoterpenoid indole alkaloid biosynthesis and C3 stereochemistry inversion.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme