Quarantine
no_smiles
Oxidation
Substrate reaction site
Product reaction site
MCS substructure diff highlighting · RDKit atom mapping
Substrate
corynantheidine
PubChem ↗
CC[C@@H]1CN2CCC3=C([C@@H]2C[C@@H]1/C(=C/OC)/C(=O)OC)NC4=CC=CC=C…
HYC3O
ΔMass: no_smiles
Missing dual SMILES or RDKit not validated
Evidence trail
Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.
Source text excerpt ation; ation; Rauvolfia tetraphylla HYC3O; purified recombinant protein; LC-MS/MS and UV confirmed.
Reaction & quality gates
- Mechanism
- Oxidation
- Evidence type
- In vitro
- Confidence
- High
- Data tier
- Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450) - Substrate class
- Other
- Product class
- Other
Literature & public identifiers
- PubMed
- PMID:41290611 ↗
- DOI
- 10.1038/s41467-025-65543-z ↗
- UniProt
- —
- GenBank
- —
- NCBI TaxID
- 545371 ↗
Ancient gene clusters govern the initiation of monoterpenoid indole alkaloid biosynthesis and C3 stereochemistry inversion.