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Quarantine no_smiles Oxidation

LtmJ

Biosynthesis of

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
terpendole E (5)
PubChem ↗ Crowdsource substrate structure
LtmJ
ΔMass: no_smiles Missing dual SMILES or RDKit not validated
Product
terpendole I (6)
PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; LtmJ catalyzes multistep oxidation; intermediate steps not fully detailed.

Reaction & quality gates

Mechanism
Oxidation
Evidence type
In vivo
Confidence
High
Data tier
Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class
Other
Product class
Other

Literature & public identifiers

PubMed
PMID:32677206 ↗
DOI
10.1002/anie.202007280 ↗
UniProt
GenBank
NCBI TaxID

Biosynthesis of Indole Diterpene Lolitrems: Radical-Induced Cyclization of an Epoxyalcohol Affording a Characteristic Lolitremane Skeleton.