CYP712K1

Tripterygium wilfordii CYP712K

Celastraceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

friedelin

PubChem ↗ C[C@H]1C(=O)CC[C@@H]2[C@@]1(CC[C@H]3[C@]2(CC[C@@]4([C@@]3(CC[C@…

CYP712K1

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

29-hydroxy-friedelan-3-one

PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; In vivo yeast assay with TwCYP712K1, feeding friedelin, producing 29-hydroxy-friedelan-3-one.

Reaction & quality gates

Mechanism: Hydroxylation
Evidence type: In vivo
Confidence: High
Data tier: Silver
mass=no_smiles; incomplete_SMILES
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:36967728 ↗
DOI: 10.46471/gigabyte.14 ↗
UniProt: WQI83062.1 ↗
GenBank: CYP712K1 ↗
NCBI TaxID: 458696 ↗

The genome of <i>Tripterygium wilfordii</i> and characterization of the celastrol biosynthesis pathway.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme