Gold
ΔMass ✓
Hydroxylation
Substrate reaction site
Product reaction site
MCS substructure diff highlighting · RDKit atom mapping
Evidence trail
Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.
Source text excerpt ation; ation; HPO catalyzes regio- and stereo-specific hydroxylation at C-2 of premnaspirodiene to form solavetivol; evidence from yeast microsome assays with NADPH.
Reaction & quality gates
- Mechanism
- Hydroxylation (+15.99 Da)
- Evidence type
- In vitro
- Confidence
- High
- Data tier
- Gold
Latin binomial + experiment + dual SMILES + ΔMass pass - Substrate class
- Other
- Product class
- Other
Literature & public identifiers
- PubMed
- PMID:17715131 ↗
- DOI
- 10.1074/jbc.m703378200 ↗
- UniProt
- A6YIH8 ↗
- GenBank
- —
- NCBI TaxID
- 35626 ↗
Functional characterization of premnaspirodiene oxygenase, a cytochrome P450 catalyzing regio- and stereo-specific hydroxylations of diverse sesquiterpene substrates.