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Silver no_smiles Reduction

ADHL1

Catharanthus roseus

Apocynaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
2,3-epoxytabersonine
PubChem ↗ CC[C@]12C[C@@]([C@H]3[C@@]4([C@H]1N(CC4)CC=C2)C5=C(N3)C=C(C=C5)…
ADHL1
ΔMass: no_smiles Missing dual SMILES or RDKit not validated
Product
3-hydroxy-2,3-dihydrotabersonine
PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ion; ion; Coupled assay with T3O and recombinant T3R; product formation dependent on both enzymes.

Reaction & quality gates

Mechanism
Reduction
Evidence type
In vitro
Confidence
High
Data tier
Silver
mass=no_smiles; incomplete_SMILES
Substrate class
Other
Product class
Other

Literature & public identifiers

PubMed
PMID:25918424 ↗
DOI
10.1073/pnas.1501821112 ↗
UniProt
KP122966 ↗
GenBank
KP122966 ↗
NCBI TaxID
4058 ↗

Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeast.