Silver
no_smiles
Hydroxylation
Substrate reaction site
Product reaction site
MCS substructure diff highlighting · RDKit atom mapping
CYP71D375
ΔMass: no_smiles
Missing dual SMILES or RDKit not validated
Evidence trail
Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.
Source text excerpt ation; ation; CYP71D375 accepts 4-methylenemiltirone (6) as substrate; product 10 inferred as 16-hydroxy-4-methylenemiltirone based on MS, retention time, and chemical logic.
Reaction & quality gates
- Mechanism
- Hydroxylation
- Evidence type
- In vitro
- Confidence
- Medium
- Data tier
- Silver
mass=no_smiles; incomplete_SMILES - Substrate class
- Other
- Product class
- Other
Literature & public identifiers
- PubMed
- PMID:33514704 ↗
- DOI
- 10.1038/s41467-021-20959-1 ↗
- UniProt
- A0A5A4JQD7 ↗
- GenBank
- —
- NCBI TaxID
- 226208 ↗
Expansion within the CYP71D subfamily drives the heterocyclization of tanshinones synthesis in Salvia miltiorrhiza.